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For this reason, patients with Parkinsons disease on levodopa therapy should avoid high B intake unless they are also taking carbidopa (which prevents this interaction)

Researchers have observed that deficiency in glutathione could be involved in the development of certain health issues including: neurodegenerative disorders such as Alzheimers, Parkinsons and Huntingtons disease, amyotrophic lateral sclerosis or motor neurone disease, and Friedreich's ataxia

However, how this change arises and contributes to HD pathogenesis is unclear

One common cause of persistent fatigue and low energy that we often see in our practice is Vitamin B12 deficiency